Additional Information
Score Description
The IPSET survival model derives from multivariate analysis of 867 patients diagnosed with essential thrombocythemia (ET) by WHO criteria. The model was validated in two independent cohorts including 132 WHO-defined ET and 234 Polycythemia vera Study-Group-defined ET patients.
Definition
Risk variables |
HR, Ci 95% |
Score 0 |
Score 1 |
Score 2 |
Age [years] |
6.5, 3.9–10.7 |
< 60 |
|
> 60 |
Leukocyte count [G/L] |
3.1, 2–4.7 |
< 11 |
> 11 |
|
Thrombosis history |
2.9, 1.9–4.5 |
no |
yes |
|
Score |
Risk category |
Median survival |
0 |
Low risk |
|
1–2 |
Intermediate risk |
17.5–24.5 years |
3–4 |
High risk |
7.1–14.7 years |
Further Reading
Passamonti F et al. A prognostic model to predict survival in 867 World Health Organization-defined essential thrombocythemia at diagnosis: a study by the International Working Group on Myelofibrosis Research and Treatment.. Blood 2012; 120 (6):1197-1201.